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Article

Development and characterization of the replicon system of Japanese encephalitis live vaccine virus SA14-14-2

26 Feb 2013

Abstract excerpt

BACKGROUND: Viral self-replicating sub-genomic replicons represent a powerful tool for studying viral genome replication, antiviral screening and chimeric vaccine development. Many kinds of flavivirus replicons have been developed with broad applications. FINDINGS: The replicon system of JEV live vaccine strain SA14-14-2 was successfully developed in this study. Two kinds of replicons that express enhanced green...

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PMID: 23442449
DOI: 10.1186/1743-422x-10-64

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