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Article

Development of a full-length cDNA-derived enterovirus A71 vaccine candidate using reverse genetics technology.

Antiviral research - 1 Aug 2016

Yang Ya-Ting, Chow Yen-Hung, Hsiao Kuang-Nan, Hu Kai-Chieh, Chiang Jen-Ron, Wu Suh-Chin, Chong Pele, Liu Chia-Chyi

Abstract excerpt

Enterovirus A71 (EV-A71) is responsible for epidemics of hand, foot and mouth disease (HFMD) in young children. To circumvent difficulties in obtaining clinical enterovirus isolates that might be contaminated with other viruses, a platform technology was developed to quickly generate vaccine virus strains based on the published enterovirus genomic sequences. A recombinant plasmid containing the full-length...

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Source

Identifiers

PMID: 27387826
DOI: 10.1016/j.antiviral.2016.06.014

Genes

SCARB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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