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Engineering a material-genetic interface as safety switch for embedded therapeutic cells

2023-04-03

Abstract excerpt

Encapsulated cell-based therapies involve the use of genetically-modified cells embedded in a material in order to produce a therapeutic agent in a specific location in the patient’s body. This approach has shown great potential in animal model systems for treating diseases such as type I diabetes or cancer, with selected approaches having been tested in clinical trials. Despite the promise shown by encapsulated c...

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Literature Corpus work
147fb213-f225-5e09-946b-ce70f247ef62
DOI
10.1101/2023.04.03.535359
Open publication

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Engineering a material-genetic interface as safety switch for embedded therapeutic cellsDOI 10.1101/2023.04.03.535359
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