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Implantable Living Materials Autonomously Deliver Therapeutics from Contained Engineered Bacteria

2025-10-10

Abstract excerpt

Microbes are increasingly utilized as living therapeutic vehicles, yet their uncontrolled dissemination in the body has long remained a roadblock to clinical development. Physical containment, while widely used for mammalian cells, remains largely unattainable due to eventual bacteria escape. Here, we present an implantable material platform that encapsulates and confines bacteria, wherein synthetically engineered...

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Identifiers and source

Literature Corpus work
f1b9c930-9eed-55bd-8b76-d303b4f26e7b
DOI
10.1101/2025.10.09.681377
Open publication

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Implantable Living Materials Autonomously Deliver Therapeutics from Contained Engineered BacteriaDOI 10.1101/2025.10.09.681377
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