Article

Polygenicity at the pathway level for anorexia nervosa

2025-10-09

Abstract excerpt

Genome-wide association studies of common disorders reveal polygenic architectures. While these variants may converge into biologically relevant pathways, how polygenicity aggregates across pathways remains unknown. We studied polygenicity at the pathway level in anorexia nervosa (AN) - a psychiatric disorder with multi-systemic clinical manifestations. We constructed pathway-based polygenic risk scores (pathway P...

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Literature Corpus work: 1450fb21-1dd5-5460-833f-eb41307bc6f0
DOI: 10.1101/2025.10.08.25337623

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