Article
Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia nervosa.
Translational psychiatry - 1 Sept 2023
Bang Lasse, Bahrami Shahram, Hindley Guy, Smeland Olav B, Rødevand Linn, Jaholkowski Piotr P, Shadrin Alexey, Connell Kevin S O', Frei Oleksandr, Lin Aihua, Rahman Zillur, Cheng Weiqiu, Parker Nadine, Fan Chun C, Dale Anders M, Djurovic Srdjan, Bulik Cynthia M, Andreassen Ole A
Abstract excerpt
Anorexia nervosa (AN) is a heritable eating disorder (50-60%) with an array of commonly comorbid psychiatric disorders and related traits. Although significant genetic correlations between AN and psychiatric disorders and related traits have been reported, their shared genetic architecture is largely understudied. We investigated the shared genetic architecture of AN and schizophrenia (SCZ), bipolar disorder...
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