Article

Reorganizing the RNA polymerase II complex for replication of an infectious noncoding RNA in vivo

2025-05-12

Abstract excerpt

DNA-dependent RNA polymerases (DdRPs) recognize not only DNA but also RNA templates. This RNA-dependent RNA polymerase (RdRP) activity is exploited by viroids in plants and human hepatitis delta virus in animals. A major knowledge gap exists regarding the molecular basis conferring this RdRP activity. Here, we provide evidence supporting the reorganization of the 12-subunit Pol II to 7-subunit in vivo for PSTVd tr...

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Literature Corpus work: 144c6268-e012-5aea-921f-f437bea9aa22
DOI: 10.1101/2025.05.12.653476

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