Article

Decitabine induces change of biological traits in myelodysplastic syndromes via FOXO1 activation

2020-08-01

Abstract excerpt

<h4>Background: </h4> Little is known about the function of tumor suppressor gene Forkhead box 1 (FOXO1) in myelodysplastic syndromes (MDS). The aim of this study was to elucidate the role of FOXO1 through decitabine (DAC) treatment. <h4>Methods: </h4>: Microarray analysis was used to identify differentially expressed genes (DEGs) from 2 MDS cell lines by DAC treatment. WebGestalt was used to perform gene ontology...

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Literature Corpus work: 1425501e-5ca2-5285-815b-e2e5c7f7bb04
DOI: 10.21203/rs.3.rs-48006/v1

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