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Distinct Gut Microbiome Landscape of PIK3CA-Mutated Colorectal Cancer: A Nationwide Pan-Cancer Genomic and Microbial Profiling Study (MONSTAR-SCREEN)

2026-05-28

Abstract excerpt

<title>Abstract</title> <p> <bold>Purpose</bold> To characterize the landscape of gut microbiota associated with oncogenic driver mutations across multiple solid tumors, with a specific focus on the clinical and biological implications of <italic>PIK3CA</italic> mutations in colorectal cancer (CRC). <bold>Methods</bold> We analyzed fecal 16S rRNA sequencing and tumor genomic profiles from 1,414 patients wit...

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Literature Corpus work: 13ed903d-4370-55fb-9ec6-8191ed44f403
DOI: 10.21203/rs.3.rs-9627410/v1

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