Article

Characterisation of SARS-CoV-2 genomic variations in response to molnupiravir treatment in the AGILE Phase IIa clinical trial.

2022-07-18

Abstract excerpt

<title>Abstract</title> <p>Molnupiravir is an antiviral approved for treating COVID-19, which is thought to drive lethal error catastrophe. How this drug-induced mechanism of action impacts the emergence of resistance mutations is unclear. AGILE Candidate Specific Trial (CST)-2 is a phase IIa trial randomising 180 adult outpatients with SARS-COV-2 infection within five days of symptom onset to molnupiravir or pla...

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Literature Corpus work: 13dbfe36-3e1a-57c2-9bbe-15234839dd1d
DOI: 10.21203/rs.3.rs-1835695/v1

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