Article

Monitoring for SARS-CoV-2 drug resistance mutations in broad viral populations

2022-05-30

Abstract excerpt

The search for drugs against COVID-19 and other diseases caused by coronaviruses focuses on the most conserved and essential proteins, mainly the main (M pro ) and the papain-like (PL pro ) proteases and the RNA-dependent RNA polymerase (RdRp). Nirmatrelvir, an inhibitor for M pro , was recently approved by FDA as a part of a two-drug combination, Paxlovid, and many more drugs are in various stages of developme...

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Literature Corpus work: 039401ec-be7e-52d7-a22e-82d8b3e817be
DOI: 10.1101/2022.05.27.493798

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