Article

Illuminating the microbiome’s dark matter: a functional genomic toolkit for the study of human gut Actinobacteria

2018-05-01

Abstract excerpt

Despite the remarkable evolutionary and metabolic diversity found within the human microbiome, the vast majority of mechanistic studies focus on two phyla: the Bacteroidetes and the Proteobacteria. Generalizable tools for studying the other phyla are urgently needed in order to transition microbiome research from a descriptive to a mechanistic discipline. Here, we focus on the Coriobacteriia class within the Actin...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 13da274d-b04b-5d2c-a587-17beecd6b7f4
DOI: 10.1101/304840

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Illuminating the microbiome’s dark matter: a functional genomic toolkit for the study of human gut ActinobacteriaDOI 10.1101/304840Read

A Genomic Toolkit for the Mechanistic Dissection of Intractable Human Gut Bacteria.Semantic proximity Read

A widespread gut bacterial lineage distinguished by redox metabolism and phage defenseSemantic proximity Read

Genome mining identifies a diversity of natural product biosynthetic capacity in human respiratory Corynebacterium strainsSemantic proximity Read

A new genomic blueprint of the human gut microbiotaSemantic proximity Read

A human gut metagenome-assembled genome catalogue spanning 41 countries supports genome-scale metabolic modelsSemantic proximity Read

Comprehensive genome analyses of <i>Sellimonas intestinalis</i> , a potential biomarker of homeostasis gut recoverySemantic proximity Read

Diversity and prevalence of <i>Anaerostipes</i> in the human gut microbiotaSemantic proximity Read

Oscillospira and related bacteria – From metagenomic species to metabolic featuresSemantic proximity Read

Culture-enriched human gut microbiomes reveal core and accessory resistance genesSemantic proximity Read

Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species and strain level diversity and evolutionSemantic proximity Read

Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution.Semantic proximity Read

Functional and Genomic Variation between Human-Derived Isolates of Lachnospiraceae Reveals Inter- and Intra-Species Diversity.Semantic proximity Read