Article
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution.
Cell host & microbe - 9 Oct 2024
Zhang Zhenrun J, Cole Cody G, Coyne Michael J, Lin Huaiying, Dylla Nicholas, Smith Rita C, Pappas Téa E, Townson Shannon A, Laliwala Nina, Waligurski Emily, Ramaswamy Ramanujam, Woodson Che, Burgo Victoria, Little Jessica C, Moran David, Rose Amber, McMillin Mary, McSpadden Emma, Sundararajan Anitha, Sidebottom Ashley M, Pamer Eric G, Comstock Laurie E
Abstract excerpt
Species of the Bacteroidales order are among the most abundant and stable bacterial members of the human gut microbiome, with diverse impacts on human health. We cultured and sequenced the genomes of 408 Bacteroidales isolates from healthy human donors representing nine genera and 35 species and performed comparative genomic, gene-specific, metabolomic, and horizontal gene transfer analyses. Families, genera, and...
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