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Genome mining identifies a diversity of natural product biosynthetic capacity in human respiratory Corynebacterium strains

21 May 2025

Abstract excerpt

ABSTRACT Corynebacterium species, integral to the healthy human upper respiratory tract (URT) microbiota, remain underexplored in microbial genomics for their potential to promote respiratory health and exclude pathobionts. This genomic study investigated the diversity and capacity for natural product synthesis within these species, as indicated by their biosynthetic gene clusters (BGCs). We aimed to map and...

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Share to Diphtheria, Corynebacterium, and Tetanus
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PMID: 40396729
DOI: 10.1128/msphere.00258-25

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