Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Genomic Toolkit for the Mechanistic Dissection of Intractable Human Gut Bacteria.

Cell host & microbe - 10 Jun 2020

Bisanz Jordan E, Soto-Perez Paola, Noecker Cecilia, Aksenov Alexander A, Lam Kathy N, Kenney Grace E, Bess Elizabeth N, Haiser Henry J, Kyaw Than S, Yu Feiqiao B, Rekdal Vayu M, Ha Connie W Y, Devkota Suzanne, Balskus Emily P, Dorrestein Pieter C, Allen-Vercoe Emma, Turnbaugh Peter J

Abstract excerpt

Despite the remarkable microbial diversity found within humans, our ability to link genes to phenotypes is based upon a handful of model microorganisms. We report a comparative genomics platform for Eggerthella lenta and other Coriobacteriia, a neglected taxon broadly relevant to human health and disease. We uncover extensive genetic and metabolic diversity and validate a tool for mapping phenotypes to genes and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actinobacteria
Share to Bacteria

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dissection

Share to Gastrointestinal Microbiome

Share to Gastrointestinal Tract

Share to Germ-Free Life

Share to Metagenome

Share to Metagenomics

Source

Open in PubMed Open full text

Identifiers

PMID: 32348781
DOI: 10.1016/j.chom.2020.04.006
PMCID: PMC7292766

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Genomic Toolkit for the Mechanistic Dissection of Intractable Human Gut Bacteria.PMID 32348781Read ↗

Illuminating the microbiome’s dark matter: a functional genomic toolkit for the study of human gut ActinobacteriaSemantic proximity Read ↗

Metabolic capabilities are highly conserved among human nasal-associated <i>Corynebacterium</i> species in pangenomic analysesSemantic proximity Read ↗

The underlying mechanisms of genetic innovation and speciation in the family Corynebacteriaceae: A phylogenomics approach.Semantic proximity Read ↗

<i>Dolosigranulum pigrum</i> cooperation and competition in human nasal microbiotaSemantic proximity Read ↗

Comparative genomic and metagenomic investigations of the <i>Corynebacterium tuberculostearicum</i> species complex reveals potential mechanisms underlying associations to skin health and diseaseSemantic proximity Read ↗

Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic miceSemantic proximity Read ↗

Revealing the diversity of commensal corynebacteria from a single human skin siteSemantic proximity Read ↗

Culturing of 'unculturable' human microbiota reveals novel taxa and extensive sporulation.Semantic proximity Read ↗

Segatella copri strains adopt distinct roles within a single individual's gutSemantic proximity Read ↗

Phenotype and multi-omics comparison of Staphylococcus and Streptococcus uncovers pathogenic traits and predicts zoonotic potential.Semantic proximity Read ↗

Moving beyond microbiome-wide associations to causal microbe identification.Semantic proximity Read ↗

Skin-associated Corynebacterium amycolatum shares cobamidesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.