Article
Cincumol prevents malignant phenotype of colorectal cancer cell line HCT116 via inhibiting PI3K/AKT signaling in vitro.
Acta cirurgica brasileira - 1 Jan 2023
Hu Gaowu, Chen Wenquan, Peng Wei, Huang Zhen, Dong Zhanlin, Cao Yongqing
Abstract excerpt
PURPOSE: Colorectal cancer (CRC) is a common human cancer along with higher incidence and mortality, and this study aimed to identify the effect of cincumol on CRC and its potential mechanisms. METHODS: CRC cell line HCT116 was used as the material. Cell proliferation was evaluated by CCK-8 assay, and cell migration was detected by scratch test and Transwell assay. TUNEL staining assay was used to evaluate cell...
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