Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-cell transcriptome analysis of Bisphenol A exposure reveals the key roles of the testicular microenvironment in male reproduction

19 Nov 2021

Abstract excerpt

Testicular development during juvenile is crucial for subsequent male reproductive function. However, it remains poorly understood about the contribution of the testis microenvironment to human germ cell maturation. Therefore, we systematically analyzed scRNA-seq transcriptome and found the dramatic changes in cell-type composition in human testis during puberty. Then we constructed cell-cell communication...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Effects and risks of endocrine disrupting chemicals
Share to Renal and related cancers
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34808557
DOI: 10.1016/j.biopha.2021.112449

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-cell transcriptome analysis of Bisphenol A exposure reveals the key roles of the testicular microenvironment in male reproductionPMID 34808557Read ↗

Environmentally-relevant doses of bisphenol A and S exposure in utero disrupt germ cell programming across generations resolved by single nucleus multi-omicsSemantic proximity Read ↗

The construction of a testis transcriptional cell atlas from embryo to adult reveals various somatic cells and their molecular rolesSemantic proximity Read ↗

Impact of endocrine disrupting chemicals and pharmaceuticals on Sertoli cell development and functionsSemantic proximity Read ↗

Mapping the Development of Human Spermatogenesis Using Transcriptomics-Based Data: A Scoping ReviewSemantic proximity Read ↗

Environmentally-relevant doses of bisphenol A and S exposure in utero disrupt germ cell programming across generations resolved by single nucleus multi-omicsSemantic proximity Read ↗

Sertoli cells are the target of environmental toxicants in the testis – a mechanistic and therapeutic insightSemantic proximity Read ↗

The Dynamic Transcriptional Cell Atlas of Testis Development during Human PubertySemantic proximity Read ↗

Unmasking the Epigenome: Insights into Testicular Cell Dynamics and Reproductive FunctionSemantic proximity Read ↗

REPRODUCTIVE TOXICOLOGY: Environmental exposures, fetal testis development and function: phthalates and beyondSemantic proximity Read ↗

Understanding testicular single cell transcriptional atlas: from developmental complications to male infertilitySemantic proximity Read ↗

Single Cell Transcriptome Sequencing of Zebrafish Testis Revealed Novel Spermatogenesis Marker Genes and Stronger Leydig-Germ Cell Paracrine InteractionsSemantic proximity Read ↗

High-content analysis of testicular toxicity of BPA and its selected analogs in mouse spermatogonial, Sertoli cells, and Leydig cells revealed BPAF induced unique multinucleation phenotype associated with the increased DNA synthesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.