Article
Multigenerational and transgenerational effects of endocrine disrupting chemicals: A role for altered epigenetic regulation?
Seminars in cell & developmental biology - 1 Jul 2015
Xin Frances, Susiarjo Martha, Bartolomei Marisa S
Abstract excerpt
Increasing evidence has highlighted the critical role of early life environment in shaping the future health outcomes of an individual. Moreover, recent studies have revealed that early life perturbations can affect the health of subsequent generations. Hypothesized mechanisms of multi- and transgenerational inheritance of abnormal developmental phenotypes include epigenetic misregulation in germ cells. In this...
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