Article

Serine 477 plays a crucial role in the interaction of the SARS-CoV-2 spike protein with the human receptor ACE2.

2020-11-13

Abstract excerpt

Since the worldwide outbreak of the infectious disease COVID-19, several studies have been published to understand the structural mechanism of the novel coronavirus SARS-CoV-2. During the infection process, the SARS-CoV-2 spike (S) protein plays a crucial role in the receptor recognition and cell membrane fusion process by interacting with the human angiotensin-converting enzyme 2 (hACE2) receptor. However, new va...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 13ae54d2-c315-5d64-a53e-ddb89903a5a5
DOI: 10.21203/rs.3.rs-106969/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Serine 477 plays a crucial role in the interaction of the SARS-CoV-2 spike protein with the human receptor ACE2.DOI 10.21203/rs.3.rs-106969/v2Read

The role of S477N mutation in the molecular behavior of SARS-CoV-2 spike protein: An in-silico perspective.Semantic proximity Read

Mutations in the receptor-binding domain of human SARS CoV-2 spike protein increases its affinity to bind human ACE-2 receptor.Semantic proximity Read

Computational prediction of the effect of mutations in the receptor-binding domain on the interaction between SARS-CoV-2 and human ACE2.Semantic proximity Read

Structural perspective of the interactions of ACE2 and SARS CoV-2 Spike protein RBDSemantic proximity Read

Analyzing the interaction of human ACE2 and RBD of spike protein of SARS-CoV-2 in perspective of Omicron variantSemantic proximity Read

In silico binding profile characterization of SARS-CoV-2 spike protein and its mutants bound to human ACE2 receptor.Semantic proximity Read

Featuring ACE2 binding SARS-CoV and SARS-CoV-2 through a conserved evolutionary pattern of amino acid residuesSemantic proximity Read

Impact of the SARS-CoV-2 S-protein G476S mutation on the interaction with human ACE-2 receptor and neutralizing antibodiesSemantic proximity Read

SARS-CoV-2 Spike mutations modify the interaction between virus Spike and human ACE2 receptors.Semantic proximity Read

Binding Interactions between Receptor-Binding Domain of Spike Protein and Human Angiotensin Converting Enzyme-2 in Omicron Variant.Semantic proximity Read

Deciphering the Impact of Mutations on the Binding Efficacy of SARS-CoV-2 Omicron and Delta Variants With Human ACE2 ReceptorSemantic proximity Read

Molecular Mechanism of the N501Y Mutation for Enhanced Binding between SARS-CoV-2’s Spike Protein and Human ACE2 ReceptorSemantic proximity Read