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In silico binding profile characterization of SARS-CoV-2 spike protein and its mutants bound to human ACE2 receptor.

Briefings in bioinformatics - 5 Nov 2021

Zhang Yuzhao, He Xibing, Zhai Jingchen, Ji Beihong, Man Viet Hoang, Wang Junmei

Abstract excerpt

Severe acute respiratory syndrome coronavirus (SARS-CoV-2), a novel coronavirus, has brought an unprecedented pandemic to the world and affected over 64 million people. The virus infects human using its spike glycoprotein mediated by a crucial area, receptor-binding domain (RBD), to bind to the human ACE2 (hACE2) receptor. Mutations on RBD have been observed in different countries and classified into nine types:...

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Identifiers

PMID: 34013346
DOI: 10.1093/bib/bbab188
PMCID: PMC8194596

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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