Article

Reelin regulates migration and differentiation of extravillous trophoblastic cells: Implications for Preeclampsia

2025-10-24

Abstract excerpt

<title>Abstract</title> <p> Background ApoER2/LRP8 is a receptor highly expressed in the placenta; however, its physiological role in this organ is little known. Reelin, an ApoER2 ligand, is an extracellular glycoprotein that participates in neuronal polarization, migration and differentiation, hence having a central role in the central nervous system (CNS) development. Upon binding to ApoER2, Reelin triggers a...

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Literature Corpus work: 1396d51f-c6f8-52d5-94db-2d0dd8b835fb
DOI: 10.21203/rs.3.rs-7934067/v1

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