Article
EP1 receptor-mediated migration of the first trimester human extravillous trophoblast: the role of intracellular calcium and calpain.
The Journal of clinical endocrinology and metabolism - 1 Aug 2005
Nicola Catalin, Timoshenko Alexander V, Dixon S Jeffrey, Lala Peeyush K, Chakraborty Chandan
Abstract excerpt
CONTEXT: The root cause of preeclampsia in the human lies in the placenta, where a subpopulation of cytotrophoblast cells called extravillous trophoblasts (EVT), known to be involved in the invasion of the uterine endometrium and utero-placental arteries, become less invasive, resulting in poor perfusion of maternal blood into placenta. OBJECTIVES: Because EVT migrate into the prostaglandin (PG) E2-rich decidua,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
