Article

Humanized CD36 mouse model supports the preclinical evaluation of therapeutic candidates targeting CD36

2023-01-10

Abstract excerpt

CD36 (also known as scavenger receptor B2) is a multifunctional receptor that mediates lipid uptake, advanced oxidation protein products, and immunological recognition, and has roles in lipid accumulation, apoptosis, as well as in metastatic colonization in cancer. CD36 is involved in tumor immunity, metastatic invasion, and therapy resistance through various molecular mechanisms. Targeting CD36 has emerged as an...

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Literature Corpus work: 138aeecc-61f7-5c05-b29f-7969a5c7c921
DOI: 10.1101/2023.01.09.523279

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