Article

Transcription factor-mediated generation of dopaminergic neurons from human iPSCs – a comparison of methods

2024-02-22

Abstract excerpt

Dopaminergic neurons are the predominant brain cells affected in Parkinson’s disease. With the limited availability of live human brain dopaminergic neurons to study pathological mechanisms of Parkinson’s disease, dopaminergic neurons have been generated from human skin cell-derived induced pluripotent stem cells. Originally, induced pluripotent stem cell-derived dopaminergic neurons were generated using small mol...

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Literature Corpus work: 137e056c-1a1c-561b-bbbc-b5304dc344b0
DOI: 10.1101/2024.02.22.581485

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