Article
Generation of eight human induced pluripotent stem cell lines from Parkinson's disease patients carrying familial mutations.
Stem cell research - 1 Jan 2020
Chen Muwan, Maimaitili Muyesier, Buchholdt Susanne Hvolbøl, Jensen Uffe Birk, Febbraro Fabia, Denham Mark
Abstract excerpt
We generated eight induced pluripotent stem cell (iPSC) lines from Parkinson's disease (PD) patients with different familial mutations using non-integrating episomal plasmids. All iPSC lines have a normal karyotype, express pluripotent genes including POU5F1, NANOG, and show alkaline phosphatase activity, as well as the ability to differentiate into all three germ layers. These PD iPSC lines can be used for...
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