Article

MHC class II is a functional receptor for H3N2 Influenza A viruses and mediates host-specificity

2025-05-02

Abstract excerpt

<title>Abstract</title> <p>Influenza A viruses (FLUAV) utilize sialic acid to enter host cells via the envelope’s hemagglutinin (HA), and its affinity for host-specific sialic acid conformations is a major host range determinant. However, some FLUAV subtypes (H17, H18, H19) were recently shown to use the major histocompatibility complex class II (MHCII) as an entry receptor instead of sialic acid (SA), challengin...

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Literature Corpus work: 135cadcb-5186-58f3-985a-36fd8f9a0acd
DOI: 10.21203/rs.3.rs-6278351/v1

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