Article

Vaccine-induced antigenic drift of a human-origin H3N2 Influenza A virus in swine alters glycan binding and sialic acid avidity

2025-12-11

Abstract excerpt

<h4>ABSTRACT</h4> Interspecies transmission of human influenza A viruses (FLUAV) to swine occurs frequently, yet the molecular factors driving adaptation remain poorly understood. Here we investigated how vaccine-induced immunity shapes the evolution of a human-origin H3N2 virus in pigs using an in vivo sustained transmission model. Pigs (seeders) were vaccinated with a commercial inactivated swine vaccine and t...

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Literature Corpus work: 6806b4d3-177b-5fff-9281-845b2c570014
DOI: 10.64898/2025.12.10.693614

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Vaccine-induced antigenic drift of a human-origin H3N2 Influenza A virus in swine alters glycan binding and sialic acid avidityDOI 10.64898/2025.12.10.693614Read

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