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Heme-dependent siderophore utilization promotes iron-restricted growth of the <i>Staphylococcus aureus hemB</i> small colony variant

2021-06-29

Abstract excerpt

The ability to acquire iron is essential for Staphylococcus aureus to cause infection. Respiration deficient S. aureus small colony variants (SCVs) frequently cause persistent infections, which necessitates they too acquire iron. How SCVs obtain iron remains unknown and so here we addressed this outstanding question by creating a stable hemB mutant in S. aureus USA300 strain LAC. The mutant, auxotrophic for he...

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Literature Corpus work
1337f492-7546-577a-9b3b-69cca63e1bcb
DOI
10.1101/2021.06.29.450315
Open publication

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Heme-dependent siderophore utilization promotes iron-restricted growth of the <i>Staphylococcus aureus hemB</i> small colony variantDOI 10.1101/2021.06.29.450315
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