Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heme-Dependent Siderophore Utilization Promotes Iron-Restricted Growth of the Staphylococcus aureus hemB Small-Colony Variant.

Journal of bacteriology - 19 Nov 2021

Batko Izabela Z, Flannagan Ronald S, Guariglia-Oropeza Veronica, Sheldon Jessica R, Heinrichs David E

Abstract excerpt

Respiration-deficient Staphylococcus aureus small-colony variants (SCVs) frequently cause persistent infections, which necessitates they acquire iron, yet how SCVs obtain iron remains unknown. To address this, we created a stable hemB mutant from S. aureus USA300 strain LAC. The hemB SCV utilized exogenously supplied hemin but was attenuated for growth under conditions of iron starvation. Transcriptome sequencing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Siderophores

Share to Staphylococcus aureus

Source

Open in PubMed Open full text

Identifiers

PMID: 34606375
DOI: 10.1128/JB.00458-21
PMCID: PMC8604074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heme-Dependent Siderophore Utilization Promotes Iron-Restricted Growth of the Staphylococcus aureus hemB Small-Colony Variant.PMID 34606375Read ↗

Heme-dependent siderophore utilization promotes iron-restricted growth of the <i>Staphylococcus aureus hemB</i> small colony variantSemantic proximity Read ↗

Staphylococcus aureus small colony variants: a challenge to microbiologists and clinicians.Semantic proximity Read ↗

The oxidative stress regulator, PerR, is required for staphyloferrin B-mediated iron acquisition in Staphylococcus aureus.Semantic proximity Read ↗

The Clinical Significance of Staphylococcus aureus Small Colony VariantsSemantic proximity Read ↗

In vivo growth of <i>Staphylococcus lugdunensis</i> is facilitated by the concerted function of heme and non-heme iron acquisition mechanismsSemantic proximity Read ↗

Role of Siderophore Biosynthesis in Virulence of Staphylococcus aureus : Identification and Characterization of Genes Involved in Production of a SiderophoreSemantic proximity Read ↗

Staphylococcus aureus small-colony variants: Formation, infection, and treatment.Semantic proximity Read ↗

The Role of Iron in Staphylococcus aureus Infection and Human Disease: A Metal Tug of War at the Host—Microbe InterfaceSemantic proximity Read ↗

Molecular Mechanisms of <i>Staphylococcus aureus</i> Iron AcquisitionSemantic proximity Read ↗

Small colony variants of Staphylococcus aureus reveal distinct protein profiles.Semantic proximity Read ↗

The Complex Intracellular Lifecycle of Staphylococcus aureus Contributes to Reduced Antibiotic Efficacy and Persistent BacteremiaSemantic proximity Read ↗

The Complex Intracellular Lifecycle of Staphylococcus aureus Contributes to Reduced Antibiotic Efficacy and Persistent BacteremiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.