Article
Small colony variants of Staphylococcus aureus reveal distinct protein profiles.
Proteomics - 1 Jun 2011
Kriegeskorte André, König Simone, Sander Gunnar, Pirkl Alexander, Mahabir Esther, Proctor Richard A, von Eiff Christof, Peters Georg, Becker Karsten
Abstract excerpt
Small-colony variants (SCVs) of Staphylococcus aureus represent a slow-growing subpopulation causing chronic and relapsing infections due to their physiological adaptation on an intracellular lifestyle. In this first proteomic study on physiological changes associated with a natural, clinically derived SCV, its proteomic profile was investigated in comparison to corresponding isogenic strains displaying normal...
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