Article

Isoform-specific roles of the <i>Drosophila</i> filamin-type protein Jitterbug (Jbug) during development

2020-10-14

Abstract excerpt

<h4>ABSTRACT</h4> Filamins are highly conserved actin-crosslinking proteins that regulate organization of the actin cytoskeleton. As key components of versatile signaling scaffolds, filamins are implicated in developmental anomalies and cancer. Multiple isoforms of filamins exist, raising the possibility of distinct functions for each isoform during development and in disease. Here, we provide an initial characte...

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Literature Corpus work: 1310b9d5-11b6-588c-aa27-6eb1e63bb6d6
DOI: 10.1101/2020.10.13.337626

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