Article

HQAlign: Aligning nanopore reads for SV detection using current-level modeling

2023-01-09

Abstract excerpt

<h4>Motivation</h4> Detection of structural variants (SV) from the alignment of sample DNA reads to the reference genome is an important problem in understanding human diseases. Long reads that can span repeat regions, along with an accurate alignment of these long reads play an important role in identifying novel SVs. Long read sequencers such as nanopore sequencing can address this problem by providing very lon...

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Literature Corpus work: 13046925-1033-5c53-95d7-c7df87896c1f
DOI: 10.1101/2023.01.08.523172

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