Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unconventional endocannabinoid signaling governs sperm activation via the sex hormone progesterone

18 Mar 2016

Abstract excerpt

Steroids regulate cell proliferation, tissue development, and cell signaling via two pathways: a nuclear receptor mechanism and genome-independent signaling. Sperm activation, egg maturation, and steroid-induced anesthesia are executed via the latter pathway, the key components of which remain unknown. Here, we present characterization of the human sperm progesterone receptor that is conveyed by the orphan enzyme...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cannabis and Cannabinoid Research
Share to Hormonal and reproductive studies
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26989199
DOI: 10.1126/science.aad6887

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unconventional endocannabinoid signaling governs sperm activation via the sex hormone progesteronePMID 26989199Read ↗

ABHD2 activity is not required for the non-genomic action of progesterone on human spermSemantic proximity Read ↗

Non-Genomic Steroid Actions in Human SpermatozoaSemantic proximity Read ↗

What Do We Know about Classical and Non-Classical Progesterone Receptors in the Human Female Reproductive Tract? A ReviewSemantic proximity Read ↗

The role of endocannabinoids in gonadal function and fertility along the evolutionary axisSemantic proximity Read ↗

Ovarian Steroids: The Good, the Bad, and the Signals that Raise ThemSemantic proximity Read ↗

CatSper: The complex main gate of calcium entry in mammalian spermatozoaSemantic proximity Read ↗

The CatSper channel mediates progesterone-induced Ca2+ influx in human spermSemantic proximity Read ↗

Nongenomic effects of progesterone on spermatozoa mechanisms of signal transduction and clinical implicationsSemantic proximity Read ↗

Jekyll and Hyde: Two Faces of Cannabinoid Signaling in Male and Female FertilitySemantic proximity Read ↗

Progesterone receptor signaling in the initiation of pregnancy and preservation of a healthy uterusSemantic proximity Read ↗

[Progesterone receptor].Semantic proximity Read ↗

The Endocannabinoid System and Its Relationship to Human ReproductionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.