Article

RNF125 Modulates Tumor Immunity by Promoting Ubiquitination of PD-L1

2021-02-08

Abstract excerpt

<title>Abstract</title> <p>In recent years, the incidence of tumors has been increasing, and the overall cure rate by traditional treatment methods does not exceed 20%. One of the most effective and promising strategies for comprehensive treatment of tumors is immunotherapy, such as treatment with the PD-1/PD-L1 antibody. Here, we showed that ring finger protein 125 (RNF125), an E3 ligase in the RING domain famil...

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Literature Corpus work: 12a4bb4f-24c3-5085-9a83-9385d1c6244d
DOI: 10.21203/rs.3.rs-167238/v1

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