Article

The Wdr5-H3K4me3 epigenetic axis regulates pancreatic tumor immunogenicity and immune suppression

2024-06-04

Abstract excerpt

<title>Abstract</title> <p>The WDR5/MLL1-H3K4me3 epigenetic axis is often activated in both tumor cells and tumor-infiltrating immune cells to drive various cellular response in the tumor microenvironment and extensively studied in hematopoietic cancer, but its respective functions in tumor cells and immune cells in the context of tumor growth regulation of solid tumor is still incompletely understood. We report...

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Literature Corpus work: 6f79f61a-eba1-53a2-a17a-e6a490aa9da0
DOI: 10.21203/rs.3.rs-4435258/v1

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