Article

Pharmacological Treatment for Neonatal Abstinence Syndrome is Associated with Altered DNA Methylation and Neurobehavior

2021-09-27

Abstract excerpt

<p>Objective: To determine whether pharmacological treatment for neonatal abstinence syndrome (NAS) is associated with changes in DNA methylation (DNAm) of the mu-opioid receptor gene (OPRM1) and improvements in neonatal neurobehavior.Study Design: Buccal swabs were collected from 37 neonates before and after morphine treatment for NAS. Genomic DNA was extracted and DNAm was examined at four CpG sites within the O...

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Literature Corpus work: 128959ee-f9cc-5987-ae07-12daf0cc03ad
DOI: 10.31234/osf.io/urhvq

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