Article

Somatic Mutations Predict Acute Myeloid Leukemia Years Before Diagnosis

2017-12-21

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Somatic mutations observed in clonal hematopoiesis are associated with increased age and risk of hematological malignancies. However, the limited number of acute myeloid leukemia (AML) patients in studies of clonal hematopoiesis thus far has precluded determination of the spectrum of mutations leading to AML and their impact on risk and time to diagnosis. <h4>Methods</h4> T...

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Literature Corpus work: 12878df8-6e45-55ed-88b0-0399abe3f4a2
DOI: 10.1101/237941

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