Article

Protein-protein interaction prediction for targeted protein degradation

2022-02-27

Abstract excerpt

Protein-protein interactions (PPIs) play a fundamental role in various biological functions; thus, detecting PPI sites is essential for understanding diseases and developing new drugs. PPI prediction is of particular relevance for the development of drugs employing targeted protein degradation, as their efficacy relies on the formation of a stable ternary complex involving two proteins. However, experimental metho...

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Literature Corpus work: 12852003-d316-56b4-84c4-9f46fe999089
DOI: 10.1101/2022.02.25.481776

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