Article

Predicting small-molecule inhibition of protein complexes

2024-08-23

Abstract excerpt

<h4>Motivation</h4> Protein-Protein Interactions (PPIs) are crucial in biological processes and disease mechanisms, underscoring the importance of discovering PPI inhibitors in drug development. Machine learning can expedite this discovery process. Although machine learning techniques for predicting general compound inhibition are available, we are not aware of any that accurately forecast the inhibitory effect o...

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Literature Corpus work: 16a84a2c-f758-52db-8012-3cb388a7128c
DOI: 10.1101/2024.08.23.609286

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