Article

Allo: Accurate allocation of multi-mapped reads enables regulatory element analysis at repeats

2023-09-15

Abstract excerpt

Transposable elements (TEs) and other repetitive regions have been shown to contain gene regulatory elements, including transcription factor binding sites. Unfortunately, regulatory elements harbored by repeats have proven difficult to characterize using short-read sequencing assays such as ChIP-seq or ATAC-seq. Most regulatory genomics analysis pipelines discard “multi-mapped” reads that align equally well to mul...

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Literature Corpus work: 123bf13c-be98-5eb0-b880-0e225be4c7c5
DOI: 10.1101/2023.09.12.556916

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