Article

The motif composition of variable-number tandem repeats impacts gene expression

2022-03-19

Abstract excerpt

Understanding the impact of DNA variation on human traits is a fundamental question in human genetics. Variable number tandem repeats (VNTRs) make up roughly 3% of the human genome but are often excluded from association analysis due to poor read mappability or divergent repeat content. While methods exist to estimate VNTR length from short-read data, it is known that VNTRs vary in both length and repeat (motif) c...

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Literature Corpus work: 01f0f46b-ec5d-5574-8fbc-4608a25147c9
DOI: 10.1101/2022.03.17.484784

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