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Genome-wide analyses of variance in blood cell phenotypes provide new insights into complex trait biology and prediction

2024-04-16

Abstract excerpt

Blood cell phenotypes are routinely tested in healthcare to inform clinical decisions. Genetic variants influencing mean blood cell phenotypes have been used to understand disease aetiology and improve prediction; however, additional information may be captured by genetic effects on observed variance. Here, we mapped variance quantitative trait loci (vQTL), i.e. genetic loci associated with trait variance, for 29...

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Literature Corpus work
121a8eaa-00bc-502e-a569-9298da37b2ec
DOI
10.1101/2024.04.15.24305830
Open publication

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Genome-wide analyses of variance in blood cell phenotypes provide new insights into complex trait biology and predictionDOI 10.1101/2024.04.15.24305830
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