Article

Polymerase chain reaction-based assays facilitate the breeding and study of mouse models of Klinefelter syndrome

2021-01-04

Abstract excerpt

Klinefelter syndrome (KS) is one of the most frequent genetic abnormalities and the leading genetic cause of non-obstructive azoospermia. The breeding of mouse models of KS and their study are essential to advance our knowledge of the pathologic mechanism. Karyotyping and fluorescence in situ hybridization are reliable methods for identifying chromosomal contents. However, technical issues associated with these m...

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Literature Corpus work: 11d7eb59-b0cc-5fe3-81cd-7042b9b42b41
DOI: 10.1101/2021.01.02.425102

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