Live Offspring from Mice Lacking the Y Chromosome Long Arm Gene Complement1

doi:10.1095/biolreprod.109.076307

Article

Live Offspring from Mice Lacking the Y Chromosome Long Arm Gene Complement1

7 May 2009

Abstract excerpt

The mouse Y chromosome long arm (Yq) comprises approximately 70 Mb of repetitive, male-specific DNA together with a short (0.7-Mb) pseudoautosomal region (PAR). The repetitive non-PAR region (NPYq) encodes genes whose deficiency leads to subfertility and infertility, resulting from impaired spermiogenesis. In XSxr(a)Y*(X) mice, the only Y-specific material is provided by the Y chromosome short arm-derived sex...

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