Article

fastCDS: proteome-scale mapping of protein domains to genomic coordinates

2026-07-22

Abstract excerpt

<h4>Summary</h4> Mapping protein regions to genomic coordinates underpins the study of exon architecture and the interpretation of clinical variants in their exon context. Existing tools resolve individual queries accurately but scale poorly to proteome-wide analyses. We present fastCDS, a C++ toolkit with command line and Python interfaces for rapid protein-to-genome coordinate mapping from GTF annotations. It m...

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Literature Corpus work: 11cb2e87-05fa-5eb1-93d8-36fbeedd4325
DOI: 10.64898/2026.07.18.739381

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