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Article

Prot2HG: a database of protein domains mapped to the human genome.

Database : the journal of biological databases and curation - 1 Jan 2020

Stanek David, Bis-Brewer Dana M, Saghira Cima, Danzi Matt C, Seeman Pavel, Lassuthova Petra, Zuchner Stephan

Abstract excerpt

Genetic variation occurring within conserved functional protein domains warrants special attention when examining DNA variation in the context of disease causation. Here we introduce a resource, freely available at www.prot2hg.com, that addresses the question of whether a particular variant falls onto an annotated protein domain and directly translates chromosomal coordinates onto protein residues. The tool can...

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Identifiers

PMID: 32293014
DOI: 10.1093/database/baz161
PMCID: PMC7157182

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