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Integrative Analysis of the Therapeutic Mechanisms of Astragaloside IV in Idiopathic Pulmonary Fibrosis via Network Pharmacology and Molecular Validation

2025-08-07

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<title>Abstract</title> <p> <bold>Background:</bold> Astragaloside IV (AS-IV), an essential active ingredient isolated from Astragalus membranaceus, has exhibited notable antifibrotic properties in diverse disease models. However, its exact role and underlying molecular mechanisms in idiopathic pulmonary fibrosis (IPF) remain insufficiently defined. <bold>Methods:</bold> In this study, we employed an integrat...

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Literature Corpus work
721f605a-9827-5862-b3fe-9a4ddd3499b8
DOI
10.21203/rs.3.rs-6797667/v1
Open publication

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Integrative Analysis of the Therapeutic Mechanisms of Astragaloside IV in Idiopathic Pulmonary Fibrosis via Network Pharmacology and Molecular ValidationDOI 10.21203/rs.3.rs-6797667/v1
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