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Identification of Hub Genes and Development of the Diagnostic Model for Lung Metastasis in Osteosarcoma through Comprehensive Bioinformatics Analysis and Machine Learning

2025-01-17

Abstract excerpt

<h4>Background: </h4> The correlation of metastatic organotropism between osteosarcoma (OS) and lung adenocarcinoma (LUAD) suggests a potential metastatic niche connecting bone and lung tumors. This study aims to analyze and identify the metastatic factors and underlying mechanisms influencing tumor behavior. Methods Data were sourced from the public repositories TCGA and TARGET. The Limma package, along with WGCN...

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Literature Corpus work
0d6ae8ab-cc07-58ba-a472-e3e767232ad2
DOI
10.22541/au.173711036.67030099/v1
Open publication

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