Article

WNT16 Elevation Induced Cell Senescence of Osteoblasts in Ankylosing Spondylitis

2021-07-20

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>WNT16 is critical for bone homeostasis, but the effect of WNT16 in ankylosing spondylitis (AS) is still unknown. Here, we investigated whether WNT16 influences bone formation and pathophysiological changes of AS in an in vitro model.<bold>Methods:</bold> Bone tissue from facet joints was obtained from five disease control and six AS patients. Primary osteoprogen...

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Literature Corpus work: 116a9c3b-6921-5970-806c-7db3fea2c4ed
DOI: 10.21203/rs.3.rs-714612/v1

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