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The ganglioside GD3 and its Synthase (ST8SIA1) as novel senescence markers associated with osteoarthritis

2025-03-25

Abstract excerpt

<h4>ABSTRACT</h4> Osteoarthritis (OA), is the most common age-induced degenerative joint disease. It is associated with synovial inflammation, subchondral bone remodeling and cartilage degradation. One of the significant emerging causes of OA progression is senescent cell accumulation within the joint compartment during lifespan. Currently, there are no therapeutic approaches nor stratification tools that rely on...

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Literature Corpus work
39655e32-a7aa-5422-834a-46beac868ae0
DOI
10.1101/2025.03.22.640206
Open publication

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